Oct 13 2020
Your Responsibilities :
You will be responsible for the design and execution of purification experiments in a large variety of R&D projects (DNA, proteins, polysaccharides, viral vector).
You will implement high-throughput and robotic technologies towards automation of purification experiments (liquid handlers, TECAN & Hamilton systems).
You will develop modelling capability and Process Analytical Technologies (PAT) for accelerating purification towards online analytics and in-silico process development.
You will investigate microfluidics and continuous alternatives for purification process steps, targeting low footprint, continuous and modular process development.
You will report the results in a comprehensive form after statistical interpretation and extensive quality check of the raw data.
You will also suggest improvements and offer perspective for further developments.
Your responsibility will also include writing experimental procedures and scientific reports, prepares and presents scientific data, defend scientific and technical decisions at the appropriate technical board, etc.
You will make sound scientific and technical decisions based on a balance of data, analysis and experience.
You will ensure proper transfer of purification processes and in-process assays to internal or external partners such as Scale-up, Clinical Manufacturing, etc.
You will ensure proactive scientific / technology watch within your own competency domain.
You will provide scientific and technical leadership in your own area of expertise and spread knowledge across the whole organization, also supporting other vaccine projects upon needs.
You will improve the process of understanding and control to meet the growing requirement by Regulatory Authorities through capability building.
You might also be responsible for the technical follow-up of external collaborations.
Basic Qualifications :
We are looking for professionals with these required skills to achieve our goals :
Ph.D. in sciences or equivalent acquired through professional experience (Chemistry, Biochemistry or Biotechnology orientation), Bio-Engineering degree, Master’s Degree in (Bio)-Chemistry or Biology.
Solid experience in purification process development (at least 4 to years in Biopharma related domain).
Demonstrated knowledge and competency in the specific area of the purification and analysis of biologic material such as DNA, proteins, polysaccharides, viral vectors.
Experience in PAT and high-throughput technologies & automated equipment (recipe setup and execution) for the purification process.
Experience with liquid handler robots (TECAN, Hamilton).
Experience in Project Management.
Good understanding of Biopharma / Vaccine development processes as well as knowledge of analytical techniques for biological material.
Good stakeholder management and excellent communication skills are necessary to meet needed mindset and behavioral changes that will be required by the business.
Fluent in spoken and written English a must. French and / or Italian a plus.
Preferred Qualifications :
If you have the following characteristics it would be a plus :
Experience in technology transfer and scale-up of drug substance processes is a plus.
Relevant experience in data interpretation and utilization, knowledge of applied statistics is an asset.
Understanding of operations & GMP manufacturing is an asset.
Ability to influence and negotiate at all levels of the organization in order to meet objective or deliverable.
Team spirit and a positive attitude.
Autonomy, scientific rigor, analytical mindset.
Good organization skills (day-to-day operations and lab management).
Ability to drive change.
Flexible thinking and be open-minded.
Strong networking skills and have scientific curiosity.